Understanding and Predicting Druggability. A High-Throughput Method for Detection of Drug Binding Sites-Reference-Cited by-同舟云学术

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Understanding and Predicting Druggability. A High-Throughput Method for Detection of Drug Binding Sites

Published:2010-07-12 Issue:15 Volume:53 Page:5858-5867
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Schmidtke Peter¹,Barril Xavier²¹

Affiliation:

1. Departament de Fisicoquímica, Facultat de Farmàcia, Universitat de Barcelona, Av. Joan XXIII s/n, 08028 Barcelona, Spain

2. Institució Catalana de Recerca i Estudis Avançats (ICREA), Institut de Biomedicina de la Universitat de Barcelona (IBUB), Barcelona, Spain

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm100574m

Reference46 articles.

1. Rediscovering the sweet spot in drug discovery

2. The druggable genome

3. A structural biology view of target drugability

4. Druggability Indices for Protein Targets Derived from NMR-Based Screening Data

5. Predicting protein druggability

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2. Predicting binding events in very flexible, allosteric, multi-domain proteins;2024-06-03

3. GTExome: Modeling commonly expressed missense mutations in the human genome;PLOS ONE;2024-05-30

4. EGPDI: identifying protein–DNA binding sites based on multi-view graph embedding fusion;Briefings in Bioinformatics;2024-05-23

5. A cross-disease, pleiotropy-driven approach for therapeutic target prioritization and evaluation;Cell Reports Methods;2024-04

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