Blood−Brain Barrier Penetration by Two Dermorphin Tetrapeptide Analogues: Role of Lipophilicity vs Structural Flexibility-Reference-Cited by-同舟云学术

Blood−Brain Barrier Penetration by Two Dermorphin Tetrapeptide Analogues: Role of Lipophilicity vs Structural Flexibility

Published:2008-03-28 Issue:8 Volume:51 Page:2571-2574
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ballet Steven¹,Misicka Aleksandra¹,Kosson Piotr¹,Lemieux Carole¹,Chung Nga N.¹,Schiller Peter W.¹,Lipkowski Andrzej W.¹,Tourwé Dirk¹

Affiliation:

1. Organic Chemistry Department, Vrije Universiteit Brussel, Pleinlaan 2, B-1050 Brussels, Belgium, Department of Chemistry, Warsaw University, Pasteura 1, 02-093 Warsaw, Poland, Medical Research Centre, Polish Academy of Sciences, Pawinskiego 5, 02-106 Warsaw, Poland, and Laboratory of Chemical Biology and Peptide Research, Clinical Research Institute of Montreal, Montreal, PQ H2W 1R7, Canada

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm701404s

Reference20 articles.

1. Glycopeptide enkephalin analogues produce analgesia in mice: evidence for penetration of the blood-brain barrier.

2. Towards control of χ-space: Conformationally constrained analogues of Phe, Tyr, Trp and His

3. N- and Cα-Methylation in Biologically Active Peptides: Synthesis, Structural and Functional Aspects

4. AMINO ACID COMPOSITION AND SEQUENCE OF DERMORPHIN, A NOVEL OPIATE-LIKE PEPTIDE FROM THE SKIN OF PHYLLOMEDUSA SAUVAGEI

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