Selectivity Determination of a Small Molecule Chemical Probe Using Protein Microarray and Affinity Capture Techniques-Reference-Cited by-同舟云学术

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Selectivity Determination of a Small Molecule Chemical Probe Using Protein Microarray and Affinity Capture Techniques

Published:2016-08-17 Issue:10 Volume:18 Page:611-615
ISSN:2156-8952
Container-title:ACS Combinatorial Science
language:en
Short-container-title:ACS Comb. Sci.

Author:

Hett Erik C.¹,Kyne Robert E.²,Gopalsamy Ariamala¹,Tones Michael A.³,Xu Hua¹,Thio Guene L.⁴,Nolan Edward⁴,Jones Lyn H.¹

Affiliation:

1. Medicine Design, Pfizer, 610 Main Street, Cambridge, Massachusetts 02139, United States

2. Medicine Design, Pfizer, East Point Road, Groton, Connecticut 06340, United States

3. Rare Disease Research Unit, Pfizer, 610 Main Street, Cambridge, Massachusetts 02139, United States

4. Protein and Cell Analysis, Life Sciences Solutions, Thermo Fisher Scientific, 5781 Van Allen Way, Carlsbad, California 92008, United States

Publisher

American Chemical Society (ACS)

Subject

General Chemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acscombsci.6b00089

Reference21 articles.

1. An industry perspective on drug target validation

2. Target validation using chemical probes

3. DcpS as a Therapeutic Target for Spinal Muscular Atrophy

4. The scavenger mRNA decapping enzyme DcpS is a member of the HIT family of pyrophosphatases

5. The human decapping scavenger enzyme DcpS modulates microRNA turnover

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