Biological and Structural Characterization of Rotamers of C–C Chemokine Receptor Type 5 (CCR5) Inhibitor GSK214096-Reference-Cited by-同舟云学术

Biological and Structural Characterization of Rotamers of C–C Chemokine Receptor Type 5 (CCR5) Inhibitor GSK214096

Published:2014-11-12 Issue:12 Volume:5 Page:1296-1299
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Kazmierski Wieslaw M.¹,Danehower Susan¹,Duan Maosheng¹,Ferris Robert G.¹,Elitzin Vassil,Minick Douglas,Sharp Matthew,Stewart Eugene,Villeneuve Manon

Affiliation:

1. Infectious Diseases TAU and ‡Platform Technology and Science, GlaxoSmithKline, Five Moore Drive, Research Triangle Park, North Carolina 27709-3398, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ml5004124

Reference27 articles.

1. Discovery of Bioavailable 4,4-Disubstituted Piperidines as Potent Ligands of the Chemokine Receptor 5 and Inhibitors of the Human Immunodeficiency Virus-1

2. Novel 4,4-Disubstituted Piperidine-Based C–C Chemokine Receptor-5 Inhibitors with High Potency against Human Immunodeficiency Virus-1 and an Improved human Ether-a-go-go Related Gene (hERG) Profile

3. Chemokine Antagonists as Therapeutics: Focus on HIV-1

4. Chemokines and cancer

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