Chemistry and Pharmacological Characterization of Novel Nitrogen Analogues of AMOP-H-OH (Sazetidine-A, 6-[5-(Azetidin-2-ylmethoxy)pyridin-3-yl]hex-5-yn-1-ol) as α4β2-Nicotinic Acetylcholine Receptor-Selective Partial Agonists-Reference-Cited by-同舟云学术

Chemistry and Pharmacological Characterization of Novel Nitrogen Analogues of AMOP-H-OH (Sazetidine-A, 6-[5-(Azetidin-2-ylmethoxy)pyridin-3-yl]hex-5-yn-1-ol) as α4β2-Nicotinic Acetylcholine Receptor-Selective Partial Agonists

Published:2010-09-07 Issue:19 Volume:53 Page:6973-6985
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Liu Jianhua¹,Eaton J. Brek²,Caldarone Barbara³,Lukas Ronald J.²,Kozikowski Alan P.¹

Affiliation:

1. Drug Discovery Program, Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, 833 South Wood Street, Chicago, Illinois 60612

2. Division of Neurobiology, Barrow Neurological Institute, 350 West Thomas Road, Phoenix, Arizona 85013

3. PsychoGenics, Inc., 765 Old Saw Mill River Road, Tarrytown, New York 10591

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm100765u

Reference53 articles.

1. Central Nicotinic Receptors: Structure, Function, Ligands, and Therapeutic Potential

2. Structural and functional diversity of native brain neuronal nicotinic receptors

3. Nicotinic acetylcholine receptors as targets for antidepressants

4. Antidepressants Noncompetitively Inhibit Nicotinic Acetylcholine Receptor Function

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