Novel 5-substituted 3-hydroxyphenyl and 3-nitrophenyl ethers of S -prolinol as α4β2-nicotinic acetylcholine receptor ligands-Reference-Cited by-同舟云学术

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Novel 5-substituted 3-hydroxyphenyl and 3-nitrophenyl ethers of S -prolinol as α4β2-nicotinic acetylcholine receptor ligands

Published:2016-12 Issue:23 Volume:26 Page:5613-5617
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Bolchi Cristiano,Bavo Francesco,Fumagalli Laura,Gotti Cecilia,Fasoli Francesca,Moretti Milena,Pallavicini Marco

Funder

CNR Research Project on Aging, and the fondazione Giancarla Vollaro

Fondazione Monzino

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference32 articles.

1. Recent Developments in Novel Antidepressants Targeting α4β2-Nicotinic Acetylcholine Receptors

2. Preclinical Studies of the Potent and Selective Nicotinic α4β2 Receptor Ligand VMY-2-95

3. Varenicline Augmentation in Depressed Smokers

4. Dissociation between duration of action in the forced swim test in mice and nicotinic acetylcholine receptor occupancy with sazetidine, varenicline, and 5-I-A85380

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1. Advances in small molecule selective ligands for heteromeric nicotinic acetylcholine receptors;Pharmacological Research;2023-08

2. Pyrrolidinyl benzofurans and benzodioxanes: Selective α4β2 nicotinic acetylcholine receptor ligands with different activity profiles at the two receptor stoichiometries;Bioorganic & Medicinal Chemistry Letters;2022-06

3. Determinants for α4β2 vs. α3β4 Subtype Selectivity of Pyrrolidine-Based nAChRs Ligands: A Computational Perspective with Focus on Recent cryo-EM Receptor Structures;Molecules;2021-06-12

4. Modifications at C(5) of 2-(2-Pyrrolidinyl)-Substituted 1,4-Benzodioxane Elicit Potent α4β2 Nicotinic Acetylcholine Receptor Partial Agonism with High Selectivity over the α3β4 Subtype;Journal of Medicinal Chemistry;2020-12-16

5. Behavioural and pharmacological profiles of zebrafish administrated pyrrolidinyl benzodioxanes and prolinol aryl ethers with high affinity for heteromeric nicotinic acetylcholine receptors;Psychopharmacology;2020-05-07

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