Enediyne C1027 Induces the Formation of Novel Covalent DNA Interstrand Cross-Links and Monoadducts
Author:
Affiliation:
1. Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School Boston, Massachusetts 02115 Institute of Medicinal Biotechnology Chinese Academy of Medical Sciences Tiantan, Beijing 100050, China
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/ja963444x
Reference15 articles.
1. (a) Goldberg, I. H.; Kappen, L. S.; Xu, Y.j.; Stassinopoulos, A.; Zeng, X.; Xi, Z.; Yang, C. F. InDNA and RNA Cleavers and Chemotherapy of Cancer and Viral Diseases; Meunier, B., Ed.; Kluwer Academic: The Netherlands, 1996; pp 1−21 and references therein.
2. Free-radical mechanisms involved in the formation of sequence-dependent bistranded DNA lesions by the antitumor antibiotics bleomycin, neocarzinostatin, and calicheamicin
3. Structure of an aromatization product of C-1027 chromophore
4. Reaction of C60 with diacyl peroxides containing perfluoroalkyl groups. The first example of electron transfer reaction via C60+· in solution
5. A Single Binding Mode of Activated Enediyne C1027 Generates Two Types of Double-Strand DNA Lesions: Deuterium Isotope-Induced Shuttling between Adjacent Nucleotide Target Sites
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