1,4-Cyclohexanecarboxylates: Potent and Selective Inhibitors of Phosophodiesterase 4 for the Treatment of Asthma-Reference-Cited by-同舟云学术

1,4-Cyclohexanecarboxylates: Potent and Selective Inhibitors of Phosophodiesterase 4 for the Treatment of Asthma

Published:1998-02-12 Issue:6 Volume:41 Page:821-835
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Christensen Siegfried B.¹,Guider Aimee¹,Forster Cornelia J.¹,Gleason John G.¹,Bender Paul E.¹,Karpinski Joseph M.¹,DeWolf, Walter E.¹,Barnette Mary S.¹,Underwood David C.¹,Griswold Don E.¹,Cieslinski Lenora B.¹,Burman Miriam¹,Bochnowicz Steven¹,Osborn Ruth R.¹,Manning Carol D.¹,Grous Marilyn¹,Hillegas Leonard M.¹,Bartus Joan O'Leary¹,Ryan M. Dominic¹,Eggleston Drake S.¹,Haltiwanger R. Curtis¹,Torphy Theodore J.¹

Affiliation:

1. Research and Development, SmithKline Beecham Pharmaceuticals, P.O. Box 1539, King of Prussia, Pennsylvania 19406-0939

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm970090r

Reference95 articles.

1. Modulation of Inflammation and Immunity by Cyclic AMP

2. Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitors

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