Structure Guided Development of Novel Thymidine Mimetics Targeting Pseudomonas aeruginosa Thymidylate Kinase: From Hit to Lead Generation-Reference-Cited by-同舟云学术

Structure Guided Development of Novel Thymidine Mimetics Targeting Pseudomonas aeruginosa Thymidylate Kinase: From Hit to Lead Generation

Published:2012-01-13 Issue:2 Volume:55 Page:852-870
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Choi Jun Yong¹,Plummer Mark S.,Starr Jeremy,Desbonnet Charlene R.,Soutter Holly,Chang Jeanne,Miller J. Richard,Dillman Keith,Miller Alita A.,Roush William R.¹

Affiliation:

1. Department of Chemistry, Scripps Florida, Jupiter, Florida 33458, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm201349f

Reference51 articles.

1. Drugs for bad bugs: confronting the challenges of antibacterial discovery

2. Nosocomial Infections Due to Multidrug-ResistantPseudomonas aeruginosa: Epidemiology and Treatment Options

3. The clinical consequences of antimicrobial resistance

4. Emerging issues in the management of infections caused by multidrug-resistant gram-negative bacteria.

5. Thymidylate kinase: The lost chemotherapeutic target

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