Double Heck Route to a Dibenzoxepine and Convergent Suzuki Cross-Coupling Strategy for the Synthesis of an MR Antagonist-Reference-Cited by-同舟云学术

Double Heck Route to a Dibenzoxepine and Convergent Suzuki Cross-Coupling Strategy for the Synthesis of an MR Antagonist

Published:2017-01-19 Issue:2 Volume:21 Page:208-217
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Hansen Marvin M.¹,Kallman Neil J.¹,Koenig Thomas M.¹,Linder Ryan J.¹,Richey Rachel N.¹,Rizzo John R.¹,Ward Jeffrey A.¹,Yu Hannah¹,Zhang Tony Y.¹,Mitchell David¹^ORCID

Affiliation:

1. Small Molecule Design and Development, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285, United States

Funder

Eli Lilly and Company

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

http://pubs.acs.org/doi/pdf/10.1021/acs.oprd.6b00368

Reference22 articles.

1. Drug Therapy of Apparent Treatment-Resistant Hypertension: Focus on Mineralocorticoid Receptor Antagonists

2. The Mineralocorticoid Receptor Promotes Fibrotic Remodeling in Atrial Fibrillation

3. Activation of the aldosterone/mineralocorticoid receptor system in chronic kidney disease and metabolic syndrome

4. Molecular pharmacology of the mineralocorticoid receptor: Prospects for novel therapeutics

5. Is there a new dawn for selective mineralocorticoid receptor antagonism?

Cited by 17 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Anwendung von Organometallkatalysatoren in der API-Synthese;Organometallik in der Prozesschemie;2024

2. Development of a Chromane-Forming Heck Reaction: Bisphosphine Mono-Oxide Mediated Regioselectivity Perturbed by Solvent-Based Peroxide Formation;Organic Process Research & Development;2023-06-07

3. Development of a Manufacturing Process toward the Convergent Synthesis of the COVID-19 Antiviral Ensitrelvir;ACS Central Science;2023-04-07

4. Recent Advances on the Development of Synthetic Strategies to Access Dibenzoxepine Derivatives;Synthesis;2022-09-27

5. Exciting progress in the transition metal‐catalyzed synthesis of oxepines, benzoxepines, dibenzoxepines, and other derivatives;Applied Organometallic Chemistry;2021-12-28