Multistep Flow Synthesis of Diazepam Guided by Droplet-Accelerated Reaction Screening with Mechanistic Insights from Rapid Mass Spectrometry Analysis
Author:
Affiliation:
1. Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, United States
Funder
Division of Chemistry
Defense Advanced Research Projects Agency
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.7b00218
Reference15 articles.
1. On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system
2. Minimizing E-factor in the continuous-flow synthesis of diazepam and atropine
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5. Applying Flow Chemistry: Methods, Materials, and Multistep Synthesis
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