Scale-Up Synthesis of Site-Specific Antibody–Drug Conjugates Using AJICAP Second-Generation Technology
Author:
Affiliation:
1. Ajinomoto Company Inc., 1-1, Suzuki-Cho, Kawasaki-Ku, Kawasaki-Shi, Kanagawa 210-8681, Japan
2. Ajinomoto Bio-Pharma Services, 11040 Roselle Street, San Diego, California 92121, United States
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.3c00111
Reference34 articles.
1. Site-selective modification strategies in antibody–drug conjugates
2. Precision Modification of Native Antibodies
3. Recent Advances in Drug–Antibody Ratio Determination of Antibody–Drug Conjugates
4. Chemical Site-Specific Conjugation Platform to Improve the Pharmacokinetics and Therapeutic Index of Antibody–Drug Conjugates
5. Site-Specific Antibody Conjugation with Payloads beyond Cytotoxins
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1. Bispecific Antibodies Produced via Chemical Site-Specific Conjugation Technology: AJICAP Second-Generation;ACS Medicinal Chemistry Letters;2023-11-21
2. Novel formats of antibody conjugates: recent advances in payload diversity, conjugation, and linker chemistry;Expert Opinion on Biological Therapy;2023-11-02
3. The Evolving Landscape of Antibody–Drug Conjugates: In Depth Analysis of Recent Research Progress;Bioconjugate Chemistry;2023-10-11
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