Manufacturing Process Development for Belzutifan, Part 4: Nitrogen Flow Criticality for Transfer Hydrogenation Control-Reference-Cited by-同舟云学术

Manufacturing Process Development for Belzutifan, Part 4: Nitrogen Flow Criticality for Transfer Hydrogenation Control

Published:2021-11-10 Issue: Volume: Page:
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Salehi Marzijarani Nastaran¹^ORCID,Fine Adam J.¹^ORCID,Dalby Stephen M.¹,Gangam Rekha²,Poudyal Samiksha¹,Behre Taylor¹,Ekkati Anil R.³,Armstrong Brittany M.¹^ORCID,Shultz C. Scott²,Dance Zachary E. X.²^ORCID,Stone Kevin¹

Affiliation:

1. Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States

2. Analytical Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States

3. Chemical Commercialization Technology, Merck & Co., Inc., Rahway, New Jersey 07065, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.1c00231

Reference40 articles.

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4. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

5. HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O 2 Sensing

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