Scalable, Telescoped Hydrogenolysis–Enzymatic Decarboxylation Process for the Asymmetric Synthesis of (R)-α-Heteroaryl Propionic Acids-Reference-Cited by-同舟云学术

Scalable, Telescoped Hydrogenolysis–Enzymatic Decarboxylation Process for the Asymmetric Synthesis of (R)-α-Heteroaryl Propionic Acids

Published:2020-10-28 Issue:3 Volume:25 Page:421-426
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Blakemore Caroline A.¹^ORCID,France Scott P.¹^ORCID,Samp Lacey²,Nason Deane M.¹,Yang Eddie¹,Howard Roger M.¹^ORCID,Coffman Karen J.¹,Yang Qingyi³^ORCID,Smith Aaron C.¹^ORCID,Evrard Edelweiss³,Li Wei⁴,Dai Linlin⁴,Yang Lixia⁴,Chen Zhiguang⁴,Zhang Qingli⁵,He Fangyan⁵,Zhang Jiesen⁵

Affiliation:

1. Medicine Design, Pfizer Inc., 445 Eastern Point Road, Groton, Connecticut 06340, United States

2. Chemical Research and Development, Pfizer Inc., 445 Eastern Point Road, Groton, Connecticut 06340, United States

3. Medicine Design, Pfizer Inc., 1 Portland Street, Cambridge, Massachusetts 02139, United States

4. BioDuro LLC, No. 233 North FuTe Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China

5. WuXi AppTec, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.0c00397

Reference31 articles.

1. Flow Chemistry: Recent Developments in the Synthesis of Pharmaceutical Products

2. Recent developments in the synthesis of optically active α-arylpropanoic acids: An important class of non-steroidal anti-inflammatory agents

3. Twenty Years of Naproxen Technology

4. Catalytic Asymmetric Synthesis Using Feedstocks: An Enantioselective Route to 2-Arylpropionic Acids and 1-Arylethyl Amines via Hydrovinylation of Vinyl Arenes

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