Use of High-Throughput Tools for Telescoped Continuous Flow Synthesis of an Alkynylnaphthyridine Anticancer Agent, HSN608-Reference-Cited by-同舟云学术

Use of High-Throughput Tools for Telescoped Continuous Flow Synthesis of an Alkynylnaphthyridine Anticancer Agent, HSN608

Published:2020-10-06 Issue:10 Volume:24 Page:2240-2251
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Biyani Shruti A.¹^ORCID,Qi Qingqing¹,Wu Jingze¹^ORCID,Moriuchi Yuta¹,Larocque Elizabeth A.¹,Sintim Herman O.¹,Thompson David H.¹^ORCID

Affiliation:

1. Department of Chemistry, Multi-disciplinary Cancer Research Facility, and Institute for Drug Discovery, Purdue University, West Lafayette, Indiana 47907, United States

Funder

National Cancer Institute

Defense Advanced Research Projects Agency

Purdue University

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.0c00289

Reference70 articles.

1. The Evolution of Chemical High-Throughput Experimentation To Address Challenging Problems in Pharmaceutical Synthesis

2. DOE (Design of Experiments) in Development Chemistry: Potential Obstacles

3. Democratizing synthesis by automation

4. Monitoring and external control of pH in microfluidic droplets during microbial culturing

5. Accelerating the drug-discovery process: new tools and technologies available to medicinal chemists

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