Stereocontrolled Synthesis of Delgocitinib, a JAK Inhibitor for the Treatment of Atopic Dermatitis-Reference-Cited by-同舟云学术

Stereocontrolled Synthesis of Delgocitinib, a JAK Inhibitor for the Treatment of Atopic Dermatitis

Published:2021-02-09 Issue:2 Volume:25 Page:342-348
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Takiguchi Hiromu¹^ORCID,Higashi Akinobu¹,Watanabe Takashi¹,Takeichi Tsubasa¹,Shimazaki Takahisa¹,Inaba Takashi¹

Affiliation:

1. Central Pharmaceutical Research Institute, Takatsuki Research Center, Japan Tobacco Inc., 1-1 Murasaki-cho, Takatsuki, Osaka 569-1125, Japan

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.1c00031

Reference22 articles.

1. Atopic dermatitis

2. Atopic Dermatitis in America Study: A Cross-Sectional Study Examining the Prevalence and Disease Burden of Atopic Dermatitis in the US Adult Population

3. Pharmacological properties of JTE-052: a novel potent JAK inhibitor that suppresses various inflammatory responses in vitro and in vivo

4. Discovery of a Janus Kinase Inhibitor Bearing a Highly Three-Dimensional Spiro Scaffold: JTE-052 (Delgocitinib) as a New Dermatological Agent to Treat Inflammatory Skin Disorders

5. a JT Receives Manufacturing and Marketing Approval of CORECTIM Ointment 0.5% for the Treatment of Atopic Dermatitis in Japan. Japan Tobacco Inc., January 23, 2020. https://www.jt.com/media/news/2020/pdf/20200123_E01.pdf (accessed 2020-12-30).

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Synthetic Approaches to the New Drugs Approved During 2020;Journal of Medicinal Chemistry;2022-07-14

2. Large-Scale Amidations in Process Chemistry: Practical Considerations for Reagent Selection and Reaction Execution;Organic Process Research & Development;2022-06-07

3. A Comprehensive Overview of Globally Approved JAK Inhibitors;Pharmaceutics;2022-05-06

4. Nucleoside Mimetics;Synthesis and Characterization of Glycosides;2022

5. Synthesis of Delgocitinib;Synfacts;2021-04-20