Identification, Characterization, Synthesis, and Strategy for Minimization of Potential Impurities Observed in the Synthesis of Solithromycin

Author:

Zhong Zhihong1,Du Chong1,Luo Zhonghua1,Song Shuaihua1,Liao Gaohong1,Yao Jia1,Goldmann Siegfried1ORCID,Wang Zhongqing12ORCID

Affiliation:

1. HEC Research and Development Center, HEC Pharm Group, Dongguan 523871, P. R. China

2. State Key Laboratory of Anti-Infective Drug Development, Sunshine Lake Pharma Co., Ltd., Dongguan 523871, P. R. China

Funder

State Key Laboratory of Anti-Infective Drug Development, Sunshine Lake Pharma Co., Ltd.

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Reference21 articles.

1. Results from the Solithromycin International Surveillance Program (2014)

2. aPereira, D. E.Patent WO 2011/146829, 2011.

3. bLiang, C.H.; Duffield, J.,U.S. Patent 2004/080391, 2004.

4. cFernandes, P. B.; Chapel, H.;Patent WO 2010/048599, 2009.

5. dPereira, D. E.U.S. Patent 2016/046660, 2016.

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