Alkali Carbonates Improve β,β-Diaryl Serine-Catalyzed Enantioselective α-Fluorination of β-Dicarbonyl Compounds
Author:
Affiliation:
1. Department of Chemistry, Biology and Marine Science, University of the Ryukyus, Senbaru 1, Nakagami, Nishihara 903-0213, Okinawa, Japan
Funder
Otsuka Chemical Co.
Okinawa Prefecture
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.joc.3c00730
Reference26 articles.
1. Fluorine in Pharmaceuticals: Looking Beyond Intuition
2. The Many Roles for Fluorine in Medicinal Chemistry
3. Next generation organofluorine containing blockbuster drugs
4. A platform for the discovery of new macrolide antibiotics
5. Identification, Characterization, Synthesis, and Strategy for Minimization of Potential Impurities Observed in the Synthesis of Solithromycin
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1. Selective Fluorination of Multi-Substituted Aldehydes or Ketones Using Amino Catalysts;Journal of Synthetic Organic Chemistry, Japan;2024-06-01
2. Synthesis of Chiral Tertiary Allylic- and Propargylic Fluorides from Nonaflates of Chiral α-Fluorinated β-Keto Dicarbonyl Compounds;The Journal of Organic Chemistry;2023-07-31
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