Implementing Continuous Manufacturing for the Final Methylation Step in the AMG 397 Process to Deliver Key Quality Attributes-Reference-Cited by-同舟云学术

Implementing Continuous Manufacturing for the Final Methylation Step in the AMG 397 Process to Deliver Key Quality Attributes

Published:2021-01-11 Issue:3 Volume:25 Page:486-499
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Tom Janine K.¹^ORCID,Achmatowicz Michal M.¹,Beaver Matthew G.²^ORCID,Colyer John¹,Ericson Ari¹,Hwang Tsang-Lin³^ORCID,Jiao Nancy³,Langille Neil F.²,Liu Min³,Lovette Michael A.¹,Sangodkar Rahul P.²,Sharvan Kumar Srividya²,Spada Simone²,Perera Damith⁴,Sheeran Jillian⁴,Campbell Kiersten⁴,Doherty Timothy⁴,Ford David D.⁴^ORCID,Fang Yuan-Qing⁴^ORCID,Rossi Emiliano⁵,Santoni Gabriella⁵,Cui Sheng²,Walker Shawn D.²^ORCID

Affiliation:

1. Drug Substance Technologies, Process Development, Amgen, Inc., Thousand Oaks, California 91320, United States

2. Drug Substance Technologies, Process Development, Amgen, Inc., Cambridge, Massachusetts 02142, United States

3. Attribute Sciences, Process Development, Amgen, Inc., Thousand Oaks, California 91320, United States

4. Snapdragon Chemistry Inc., Waltham, Massachusetts 02451, United States

5. F.I.S.-Fabbrica Italiana Sintetici S.p.A., Viale Milano 26, 36075 Montecchio Maggiore, Vincenza

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.0c00440

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