A Continuous Process for Manufacturing Apremilast. Part II: Process Characterization to Establish a Parametric Control Strategy-Reference-Cited by-同舟云学术

A Continuous Process for Manufacturing Apremilast. Part II: Process Characterization to Establish a Parametric Control Strategy

Published:2024-02-13 Issue:5 Volume:28 Page:1385-1401
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Griffin Daniel J.¹^ORCID,Hsieh Hsiao-Wu¹^ORCID,Avci Nadide Hazal¹,Sarkar Nandini²,Fostinis James D.¹^ORCID,Klitzing Nicholas³,Murray James I.³^ORCID,Wimalasinghe Rasangi²,Spada Simone¹,Zeng Alicia²,Beaver Matthew G.¹^ORCID

Affiliation:

1. Drug Substance Technologies − Synthetics, Amgen, Inc., Cambridge, Massachusetts 02142, United States

2. Pivotal Attribute Sciences, Amgen, Inc., Cambridge, Massachusetts 02142, United States

3. Drug Substance Technologies − Synthetics, Amgen, Inc., Thousand Oaks, California 91320, United States

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.3c00403

Reference52 articles.

1. A field guide to flow chemistry for synthetic organic chemists

2. Towards the Standardization of Flow Chemistry Protocols for Organic Reactions

3. Review: Continuous Manufacturing of Small Molecule Solid Oral Dosage Forms

4. Overcoming the Hurdles and Challenges Associated with Developing Continuous Industrial Processes

5. A Perspective on Continuous Flow Chemistry in the Pharmaceutical Industry

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