A Biocatalytic Route to the Novel Antiepileptic Drug Brivaracetam
Author:
Affiliation:
1. Chemical Process Research and Development, Pharma Sciences, UCB Pharma S.A., Chemin du Foriest, 1420 Braine l’Alleud, Belgium
Funder
Direction Générale Opérationnelle de l'Économie, de l'Emploi et de la Recherche, Région Wallonne
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.6b00094
Reference8 articles.
1. Discovery of 4-Substituted Pyrrolidone Butanamides as New Agents with Significant Antiepileptic Activity
2. Progress report on new antiepileptic drugs: A summary of the Eleventh Eilat Conference (EILAT XI)
3. A randomized, double‐blind, placebo‐controlled, multicenter, parallel‐group study to evaluate the efficacy and safety of adjunctive brivaracetam in adult patients with uncontrolled partial‐onset seizures
4. An open-label, prospective, exploratory study of patients with epilepsy switching from levetiracetam to brivaracetam
5. Practical Synthesis of BILA 2157 BS, a Potent and Orally Active Renin Inhibitor: Use of an Enzyme-Catalyzed Hydrolysis for the Preparation of Homochiral Succinic Acid Derivatives
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