Practical Synthesis of BILA 2157 BS, a Potent and Orally Active Renin Inhibitor: Use of an Enzyme-Catalyzed Hydrolysis for the Preparation of Homochiral Succinic Acid Derivatives-Reference-Cited by-同舟云学术

Practical Synthesis of BILA 2157 BS, a Potent and Orally Active Renin Inhibitor: Use of an Enzyme-Catalyzed Hydrolysis for the Preparation of Homochiral Succinic Acid Derivatives

Published:1999-08-11 Issue:18 Volume:64 Page:6622-6634
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Beaulieu Pierre L.¹,Gillard James¹,Bailey Murray¹,Beaulieu Christian¹,Duceppe Jean-Simon¹,Lavallée Pierre¹,Wernic Dominik¹

Affiliation:

1. Boehringer Ingelheim (Canada) Ltd., Bio-Méga Research Division, 2100 Cunard Street, Laval, Québec, Canada, H7S 2G5

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo990321x

Reference29 articles.

1. Renin inhibitors

2. Discovery of non-peptidic P 2 –P 3 butanediamide renin inhibitors with high oral efficacy

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