Development of a Practical Synthesis of a Peripherally Selective Noradrenaline Reuptake Inhibitor Possessing a Chiral 6,7-trans-Disubstituted-1,4-oxazepane as a Scaffold-Reference-Cited by-同舟云学术

Development of a Practical Synthesis of a Peripherally Selective Noradrenaline Reuptake Inhibitor Possessing a Chiral 6,7-trans-Disubstituted-1,4-oxazepane as a Scaffold

Published:2017-11-13 Issue:12 Volume:21 Page:2001-2011
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Ishimoto Kazuhisa¹^ORCID,Yamaguchi Kotaro¹,Nishimoto Atsushi¹,Murabayashi Mika¹,Ikemoto Tomomi¹

Affiliation:

1. Process Chemistry, Pharmaceutical Sciences, Takeda Pharmaceutical Company Limited, 17-85, Jusohonmachi 2-Chome, Yodogawa-ku, Osaka 532-8686, Japan

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.7b00313

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4. Design, synthesis and biological evaluation of a novel series of peripheral-selective noradrenaline reuptake inhibitor

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