Redesign of a Grignard-Based Active Pharmaceutical Ingredient (API) Batch Synthesis to a Flow Process for the Preparation of Melitracen HCl
Author:
Affiliation:
1. H. Lundbeck A/S, Oddenvej 182, 4500 Nykøbing Sjælland, Denmark
2. Department of Chemical and Biochemical Engineering, Technical University of Denmark, DTU, Building 229, 2800 Kgs. Lyngby, Denmark
Funder
H. Lundbeck A/S
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.7b00368
Reference45 articles.
1. Improving Pharmaceutical Product Development and Manufacturing: Impact on Cost of Drug Development and Cost of Goods Sold of Pharmaceuticals
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5. Key Green Engineering Research Areas for Sustainable Manufacturing: A Perspective from Pharmaceutical and Fine Chemicals Manufacturers
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