Development of a Telescoped Alkylation/Reduction Reaction Sequence and an Asymmetric Hydrogenation to Enable the Kilogram Synthesis of ABBV-3748-Reference-Cited by-同舟云学术

Development of a Telescoped Alkylation/Reduction Reaction Sequence and an Asymmetric Hydrogenation to Enable the Kilogram Synthesis of ABBV-3748

Published:2022-09-29 Issue:10 Volume:26 Page:2947-2956
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Kallemeyn Jeffrey M.¹^ORCID,Hartung John¹^ORCID,Connolly Timothy¹,Ickes Andrew¹,Kotecki Brian¹,Van Haandel Leon²,Nazari Milad²,Manjrekar Onkar¹,Chen Shuang¹^ORCID

Affiliation:

1. Process Research and Development, AbbVie, Inc., 1 N. Waukegan Road, North Chicago, Illinois 60064, United States

2. Analytical Research and Development, AbbVie, Inc., 1 N. Waukegan Road, North Chicago, Illinois 60064, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.2c00245

Reference22 articles.

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2. Worldwide rates of diagnosis and effective treatment for cystic fibrosis

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