Streamlined Synthesis of a Bicyclic Amine Moiety Using an Enzymatic Amidation and Identification of a Novel Solid Form-Reference-Cited by-同舟云学术

Streamlined Synthesis of a Bicyclic Amine Moiety Using an Enzymatic Amidation and Identification of a Novel Solid Form

Published:2021-05-27 Issue:6 Volume:25 Page:1419-1430
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Brown Maria S.¹,Caporello Michaella A.¹,Goetz Adam E.¹^ORCID,Johnson Amber M.¹,Jones Kris N.¹,Knopf Kevin M.¹,Kulkarni Samir A.¹,Lee Taegyo¹,Li Bryan¹^ORCID,Lu Cuong V.¹,Magano Javier¹^ORCID,Puchlopek-Dermenci Angela L. A.¹,Reyes Giselle P.¹,Ruggeri Sally Gut¹,Wei Lulin¹,Weisenburger Gerald A.¹,Wisdom Richard A.²,Zhang Mengtan³

Affiliation:

1. Chemical Research and Development, Pfizer Worldwide Research and Development, Groton Laboratories, Eastern Point Road, Groton, Connecticut 06340, United States

2. Euticals GmbH, Industriepark Höchst, D 569, 65926 Frankfurt am Main, Germany

3. Analytical Research and Development, Pfizer Worldwide Research and Development, Groton Laboratories, Eastern Point Road, Groton, Connecticut 06340, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.1c00120

Reference69 articles.

1. Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

2. Escape from Flatland 2: complexity and promiscuity

3. Pharmaceuticals that contain polycyclic hydrocarbon scaffolds

4. Saturated bioisosteres of benzene: where to go next?

5. Fsp3-rich and diverse fragments inspired by natural products as a collection to enhance fragment-based drug discovery

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