Molecular Scaffolds with High Propensity to Form Multi-Target Activity Cliffs-Reference-Cited by-同舟云学术

Molecular Scaffolds with High Propensity to Form Multi-Target Activity Cliffs

Published:2010-04-02 Issue:4 Volume:50 Page:500-510
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Hu Ye¹,Bajorath Jürgen¹

Affiliation:

1. Department of Life Science Informatics, B-IT, LIMES Program Unit Chemical Biology and Medicinal Chemistry, Rheinische Friedrich-Wilhelms-Universität, Dahlmannstr. 2, D-53113 Bonn, Germany

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ci100059q

Reference36 articles.

1. The Properties of Known Drugs. 1. Molecular Frameworks

2. Chemical substructures in drug discovery

3. On Scaffolds and Hopping in Medicinal Chemistry

4. Scaffold selection and scaffold hopping in lead generation: a medicinal chemistry perspective

5. Drug and Drug Candidate Building Block Analysis

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