Synthesis, Molecular Editing, and Biological Assessment of the Potent Cytotoxin Leiodermatolide-Reference-Cited by-同舟云学术

Synthesis, Molecular Editing, and Biological Assessment of the Potent Cytotoxin Leiodermatolide

Published:2014-10-27 Issue:44 Volume:136 Page:15719-15729
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Mailhol Damien¹,Willwacher Jens¹,Kausch-Busies Nina¹,Rubitski Elizabeth E.²,Sobol Zhanna²,Schuler Maik²,Lam My-Hanh³,Musto Sylvia³,Loganzo Frank³,Maderna Andreas⁴,Fürstner Alois¹

Affiliation:

1. Max-Planck-Institut für Kohlenforschung, D-45470 Mülheim/Ruhr, Germany

2. Pfizer Drug Safety Research and Development, 445 Eastern Point Road, Groton, Connecticut 06340, United States

3. Pfizer Oncology, 401 North Middletown Road, Pearl River, New York 10965, United States

4. Pfizer Oncology Medicinal Chemistry, 445 Eastern Point Road, Groton, Connecticut 06340, United States

Funder

Verband der Chemischen Industrie

Max-Planck-Gesellschaft

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja508846g

Reference103 articles.

1. Leiodermatolide, a Potent Antimitotic Macrolide from the Marine Sponge Leiodermatium sp.

2. bWright, A. E.; Reed, J. K.; Roberts, J.; Longley, R. E.U. S. Pat. Appl. Publ. US 20080033035 A1 20080207, 2008.

3. Anticancer Agents from Natural Products

4. Anticancer drugs from nature—natural products as a unique source of new microtubule-stabilizing agents

5. Recent progress with microtubule stabilizers: new compounds, binding modes and cellular activities

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