Pharmacokinetics and Pharmacodynamics of Phase II Drug Metabolizing/Antioxidant Enzymes Gene Response by Anticancer Agent Sulforaphane in Rat Lymphocytes-Reference-Cited by-同舟云学术

Pharmacokinetics and Pharmacodynamics of Phase II Drug Metabolizing/Antioxidant Enzymes Gene Response by Anticancer Agent Sulforaphane in Rat Lymphocytes

Published:2012-09-11 Issue:10 Volume:9 Page:2819-2827
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Wang Hu¹,Khor Tin Oo¹,Yang Qian¹,Huang Ying¹,Wu Tien-yuan¹,Saw Constance Lay-Lay¹,Lin Wen¹,Androulakis Ioannis P.¹,Kong Ah-Ng Tony¹

Affiliation:

1. Graduate Program in Pharmaceutical Sciences, Department of Pharmaceutics, Ernest Mario School of Pharmacy, ‡Center for Cancer Prevention Research, Department of Pharmaceutics, Ernest Mario School of Pharmacy, §Departments of Chemical and Biochemical Engineering, and ∥Department of Biomedical Engineering, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/mp300130k

Reference47 articles.

1. Isothiocyanates as Cancer Chemopreventive Agents: Their Biological Activities and Metabolism in Rodents and Humans

2. A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure.

3. The chemical diversity and distribution of glucosinolates and isothiocyanates among plants

4. Sulforaphane- and Phenethyl Isothiocyanate–Induced Inhibition of Aflatoxin B1–Mediated Genotoxicity in Human Hepatocytes: Role of GSTM1 Genotype and CYP3A4 Gene Expression

5. Induction of phase I, II and III drug metabolism/transport by xenobiotics

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