A Practical, Component-Based Synthetic Route to Methylthiolincosamine Permitting Facile Northern-Half Diversification of Lincosamide Antibiotics-Reference-Cited by-同舟云学术

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A Practical, Component-Based Synthetic Route to Methylthiolincosamine Permitting Facile Northern-Half Diversification of Lincosamide Antibiotics

Published:2021-04-30 Issue:18 Volume:143 Page:6829-6835
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Mitcheltree Matthew J.¹^ORCID,Stevenson Jack W.¹^ORCID,Pisipati Amarnath¹,Myers Andrew G.¹^ORCID

Affiliation:

1. Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, United States

Funder

LEO Fondet

Blavatnik Biomedical Accelerator at Harvard University

Harvard College Research Program

National Science Foundation Graduate Research Fellowship

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.1c03536

Reference59 articles.

1. Chemical Studies on Lincomycin. I. The Structure of Lincomycin

2. Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria

3. Structures of MLSBK Antibiotics Bound to Mutated Large Ribosomal Subunits Provide a Structural Explanation for Resistance

4. Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action

5. Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus

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1. Total Synthesis and Stereochemical Assignment of Enteropeptin A;Journal of the American Chemical Society;2024-06-23

2. An antibiotic preorganized for ribosomal binding overcomes antimicrobial resistance;Science;2024-02-16

3. Lincosamide Antibiotics: Structure, Activity, and Biosynthesis;ChemBioChem;2024-01-15

4. Divergent synthesis of nitrocyclopropanes and isoxazoline N-oxides from nitro compounds and vinyl sulfonium salts;Organic Chemistry Frontiers;2024

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