Exploring Electrochemical C(sp<sup>3</sup>)–H Oxidation for the Late-Stage Methylation of Complex Molecules-Reference-Cited by-同舟云学术

Exploring Electrochemical C(sp³)–H Oxidation for the Late-Stage Methylation of Complex Molecules

Published:2022-01-11 Issue:3 Volume:144 Page:1187-1197
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Novaes Luiz F. T.¹^ORCID,Ho Justin S. K.¹,Mao Kaining¹,Liu Kaida²,Tanwar Mayank²,Neurock Matthew²,Villemure Elisia³^ORCID,Terrett Jack A.³^ORCID,Lin Song¹^ORCID

Affiliation:

1. Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14850, United States

2. Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, Minnesota 55455, United States

3. Department of Discovery Chemistry, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States

Funder

Division of Chemistry

Genentech

U.S. Department of Defense

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.1c09412

Reference60 articles.

1. The Methylation Effect in Medicinal Chemistry

2. Profound Methyl Effects in Drug Discovery and a Call for New CH Methylation Reactions

3. Installing the “magic methyl” – C–H methylation in synthesis

4. Analysis of Past and Present Synthetic Methodologies on Medicinal Chemistry: Where Have All the New Reactions Gone?

5. TRP Channels and Pain

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