Photoenzymatic Synthesis of α-Tertiary Amines by Engineered Flavin-Dependent “Ene”-Reductases-Reference-Cited by-同舟云学术

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Photoenzymatic Synthesis of α-Tertiary Amines by Engineered Flavin-Dependent “Ene”-Reductases

Published:2021-11-16 Issue:47 Volume:143 Page:19643-19647
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Gao Xin¹,Turek-Herman Joshua R.¹²,Choi Young Joo¹,Cohen Ryan D.³^ORCID,Hyster Todd K.¹²^ORCID

Affiliation:

1. Department of Chemistry, Princeton University, Princeton, New Jersey 08544, United States

2. Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14853, United States

3. Analytical Research & Development, Merck & Company Inc., Rahway, New Jersey 07065, United States

Funder

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.1c09828

Reference39 articles.

1. Improving Drug Candidates by Design: A Focus on Physicochemical Properties As a Means of Improving Compound Disposition and Safety

2. Recognizing molecules with drug-like properties

3. Stereoselective Formation of Amines

4. Asymmetric Hydrogenation of N-Sulfonylated-α-dehydroamino Acids: Toward the Synthesis of an Anthrax Lethal Factor Inhibitor

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