Synthesis and Antiribosomal Activities of 4′-O-, 6′-O-, 4″-O-, 4′,6′-O- and 4″,6″-O-Derivatives in the Kanamycin Series Indicate Differing Target Selectivity Patterns between the 4,5- and 4,6-Series of Disubstituted 2-Deoxystreptamine Aminoglycoside Antibiotics-Reference-Cited by-同舟云学术

Synthesis and Antiribosomal Activities of 4′-O-, 6′-O-, 4″-O-, 4′,6′-O- and 4″,6″-O-Derivatives in the Kanamycin Series Indicate Differing Target Selectivity Patterns between the 4,5- and 4,6-Series of Disubstituted 2-Deoxystreptamine Aminoglycoside Antibiotics

Published:2015-08-06 Issue:10 Volume:1 Page:479-486
ISSN:2373-8227
Container-title:ACS Infectious Diseases
language:en
Short-container-title:ACS Infect. Dis.

Author:

Kato Takayuki¹,Yang Guanyu¹,Teo Youjin²,Juskeviciene Reda²,Perez-Fernandez Déborah³,Shinde Harish M.³,Salian Sumanth³,Bernet Bruno³,Vasella Andrea³,Böttger Erik C.²,Crich David¹

Affiliation:

1. Department of Chemistry, Wayne State University, Detroit, Michigan 48202, United States

2. Institut für Medizinische Mikrobiologie, Universität Zürich, 8006 Zürich, Switzerland

3. Laboratorium für Organische Chemie, ETH Zürich, 8093 Zürich, Switzerland

Funder

Syngenta AG

Universität Zürich

Wayne State University

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases