Identification via a Parallel Hit Progression Strategy of Improved Small Molecule Inhibitors of the Malaria Purine Uptake Transporter that Inhibit Plasmodium falciparum Parasite Proliferation
Author:
Affiliation:
1. Platform Technology & Science and Discovery Partners in Academia, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania 19426, United States
Funder
National Institute of Allergy and Infectious Diseases
GlaxoSmithKline
Publisher
American Chemical Society (ACS)
Subject
Infectious Diseases
Link
https://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.9b00168
Reference63 articles.
1. (2016) WHO Global Malaria Programme: World Malaria Report 2016, World Health Organization, Geneva, Switzerland.
2. Spread of Artemisinin Resistance in Plasmodium falciparum Malaria
3. Understanding artemisinin-resistant malaria
4. Evidence of Artemisinin-Resistant Plasmodium falciparum Malaria in Eastern India
5. pfk13 -Independent Treatment Failure in Four Imported Cases of Plasmodium falciparum Malaria Treated with Artemether-Lumefantrine in the United Kingdom
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3. Transporter-Mediated Solutes Uptake as Drug Target in Plasmodium falciparum;Frontiers in Pharmacology;2022-02-07
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