Targeting Bacterial Sortase A with Covalent Inhibitors: 27 New Starting Points for Structure-Based Hit-to-Lead Optimization-Reference-Cited by-同舟云学术

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Targeting Bacterial Sortase A with Covalent Inhibitors: 27 New Starting Points for Structure-Based Hit-to-Lead Optimization

Published:2019-11-14 Issue:2 Volume:6 Page:186-194
ISSN:2373-8227
Container-title:ACS Infectious Diseases
language:en
Short-container-title:ACS Infect. Dis.

Author:

Jaudzems Kristaps¹²^ORCID,Kurbatska Viktorija³,Je̅kabsons Atis¹,Bobrovs Raitis¹^ORCID,Rudevica Zhanna³,Leonchiks Ainars³^ORCID

Affiliation:

1. Latvian Institute of Organic Synthesis, Aizkraukles 21, Riga LV-1006, Latvia

2. Department of Organic Chemistry, University of Latvia, Jelgavas 1, Riga LV-1004, Latvia

3. Latvian Biomedical Research and Study Centre, Ratsupites 1 k1, Riga LV-1067, Latvia

Funder

European Regional Development Fund

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

Link

https://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.9b00265

Reference36 articles.

1. Changes in the Epidemiology of Methicillin-Resistant Staphylococcus aureus in Intensive Care Units in US Hospitals, 1992-2003

2. Survey of Infections Due toStaphylococcusSpecies: Frequency of Occurrence and Antimicrobial Susceptibility of Isolates Collected in the United States, Canada, Latin America, Europe, and the Western Pacific Region for the SENTRY Antimicrobial Surveillance Program, 1997–1999

3. Infections caused by Gram-positive bacteria: a review of the global challenge

4. Meticillin-resistant Staphylococcus aureus (MRSA): global epidemiology and harmonisation of typing methods

5. Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

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1. Mechanistic Analysis of 5-Hydroxy γ-Pyrones as Michael Acceptor Prodrugs;The Journal of Organic Chemistry;2024-08-23

2. Sortases: structure, mechanism, and implications for protein engineering;Trends in Biochemical Sciences;2024-07

3. The Complete Assessment of Small Molecule and Peptidomimetic Inhibitors of Sortase A Towards Antivirulence Treatment;Chemistry – A European Journal;2024-06-19

4. Emerging and Re-emerging Warheads for Targeted Covalent Inhibitors: An Update;Journal of Medicinal Chemistry;2024-05-07

5. Covalent hits and where to find them;SLAS Discovery;2024-04

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