Environmental Toxicant Exposure Paralyzes Human Placental Macrophage Responses to Microbial Threat

Author:

Stephens Victoria R.1,Moore Rebecca E.2,Spicer Sabrina K.3,Talbert Julie A.3,Lu Jacky145,Chinni Riya6,Chambers Schuyler A.37ORCID,Townsend Steven D.3ORCID,Manning Shannon D.8,Rogers Lisa M.9,Aronoff David M.9ORCID,Vue Zer10,Neikirk Kit10,Hinton Antentor O.10,Damo Steven M.111213,Noble Kristen N.14,Eastman Alison J.15,McCallister Monique M.16,Osteen Kevin G.1151718,Gaddy Jennifer A.12618ORCID

Affiliation:

1. Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, United States

2. Department of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, Tennessee 37232, United States

3. Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37240, United States

4. Department of Pathology, Stanford University, Palo Alto, California 94304, United States

5. Department of Pathology and Laboratory Medicine, Children’s Hospital of Los Angeles, Los Angeles, California 90027, United States

6. Department of Medicine, Health, and Society, Vanderbilt University, Nashville, Tennessee 37235, United States

7. Department of Chemistry, Stanford University, Palo Alto, California 94305, United States

8. Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan 48824, United States

9. Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, United States

10. Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee 37232, United States

11. Department of Biochemistry, Vanderbilt University, Nashville, Tennessee 37205, United States

12. Center for Structural Biology, Vanderbilt University, Nashville, Tennessee 37205, United States

13. Department of Life and Physical Sciences, Fisk University, Nashville, Tennessee 37208, United States

14. Department of Pediatrics, Vanderbilt University Medical Center Nashville, Tennessee 37232, United States

15. Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, United States

16. Department of Biological Sciences, Tennessee State University, Nashville, Tennessee 37209, United States

17. Department of Obstetrics and Gynecology, Meharry Medical College, Nashville, Tennessee 37208, United States

18. Tennessee Valley Health Systems, Department of Veterans Affairs, Nashville, Tennessee 37212, United States

Funder

National Institute of Environmental Health Sciences

Division of Chemistry

National Institute of Diabetes and Digestive and Kidney Diseases

National Heart, Lung, and Blood Institute

National Institute of Allergy and Infectious Diseases

National Institute of Child Health and Human Development

Camille and Henry Dreyfus Foundation

U.S. Environmental Protection Agency

Bristol-Myers Squibb

Dartmouth College

United Negro College Fund

Burroughs Wellcome Fund

Division of Equity for Excellence in STEM

Vanderbilt Diabetes Research and Training Center, Vanderbilt University Medical Center

U.S. Department of Veterans Affairs

Alfred P. Sloan Foundation

Chan Zuckerberg Initiative

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

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