Chemical Optimization of Selective <i>Pseudomonas aeruginosa</i> LasB Elastase Inhibitors and Their Impact on LasB-Mediated Activation of IL-1β in Cellular and Animal Infection Models-Reference-Cited by-同舟云学术

Chemical Optimization of Selective Pseudomonas aeruginosa LasB Elastase Inhibitors and Their Impact on LasB-Mediated Activation of IL-1β in Cellular and Animal Infection Models

Published:2023-01-20 Issue:2 Volume:9 Page:270-282
ISSN:2373-8227
Container-title:ACS Infectious Diseases
language:en
Short-container-title:ACS Infect. Dis.

Author:

Everett Martin J.¹^ORCID,Davies David T.¹^ORCID,Leiris Simon¹,Sprynski Nicolas¹^ORCID,Llanos Agustina¹,Castandet Jérôme M.¹^ORCID,Lozano Clarisse¹,LaRock Christopher N.²^ORCID,LaRock Doris L.²,Corsica Giuseppina³,Docquier Jean-Denis³⁴,Pallin Thomas D.⁵^ORCID,Cridland Andrew⁵,Blench Toby⁵^ORCID,Zalacain Magdalena¹,Lemonnier Marc¹^ORCID

Affiliation:

1. Antabio SAS, Biostep, 436 rue Pierre et Marie Curie, 31670 Labège, France

2. Department of Microbiology and Immunology, Rollins Research Center, 1510 Clifton Rd, Atlanta, Georgia 30322, United States

3. Dipartimento di Biotecnologie Mediche, Università degli Studi di Siena, Viale Bracci 16, 53100 Siena, Italy

4. Centre d’Ingénierie des Protéines - InBioS, University of Liège, Allée du six Août 11, 4000 Liège, Belgium

5. Charles River Laboratories, 8-9 The Spire Green Centre, Harlow, Essex CM19 5TR, U.K.

Funder

Wellcome Trust

U.S. Department of Health and Human Services

Publisher

American Chemical Society (ACS)

Subject