Cystic Fibrosis and Pseudomonas aeruginosa: the Host-Microbe Interface-Reference-Cited by-同舟云学术

Cystic Fibrosis and Pseudomonas aeruginosa: the Host-Microbe Interface

Published:2019-06-19 Issue:3 Volume:32 Page:
ISSN:0893-8512
Container-title:Clinical Microbiology Reviews
language:en
Short-container-title:Clin Microbiol Rev

Author:

Malhotra Sankalp¹²,Hayes Don²³⁴,Wozniak Daniel J.²⁴⁵

Affiliation:

1. Department of Microbial Infection and Immunity, The Ohio State University, Columbus, Ohio, USA

2. The Ohio State University College of Medicine, Columbus, Ohio, USA

3. Department of Pediatrics, The Ohio State University, Columbus, Ohio, USA

4. Section of Pulmonary Medicine, Nationwide Children’s Hospital, Columbus, Ohio, USA

5. Department of Microbiology, The Ohio State University, Columbus, Ohio, USA

Abstract

In human pathophysiology, the clash between microbial infection and host immunity contributes to multiple diseases. Cystic fibrosis (CF) is a classical example of this phenomenon, wherein a dysfunctional, hyperinflammatory immune response combined with chronic pulmonary infections wreak havoc upon the airway, leading to a disease course of substantial morbidity and shortened life span.

Funder

HHS | National Institutes of Health

OSU | Center for Clinical and Translational Science, Ohio State University

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Microbiology (medical),Public Health, Environmental and Occupational Health,General Immunology and Microbiology,Epidemiology

Link

https://journals.asm.org/doi/pdf/10.1128/CMR.00138-18

Reference457 articles.

1. Cystic fibrosis

2. Cystic Fibrosis Foundation. 2017. Cystic Fibrosis Foundation patient registry. 2016 annual data report. Cystic Fibrosis Foundation, Bethesda, MD.