Synthesis and Testing of Analogs of the Tuberculosis Drug Candidate SQ109 against Bacteria and Protozoa: Identification of Lead Compounds against <i>Mycobacterium abscessus</i> and Malaria Parasites-Reference-Cited by-同舟云学术

Synthesis and Testing of Analogs of the Tuberculosis Drug Candidate SQ109 against Bacteria and Protozoa: Identification of Lead Compounds against Mycobacterium abscessus and Malaria Parasites

Published:2023-01-27 Issue:2 Volume:9 Page:342-364
ISSN:2373-8227
Container-title:ACS Infectious Diseases
language:en
Short-container-title:ACS Infect. Dis.

Author:

Stampolaki Marianna¹,Malwal Satish R.²^ORCID,Alvarez-Cabrera Nadine³,Gao Zijun²^ORCID,Moniruzzaman Mohammad⁴,Babii Svitlana O.⁴,Naziris Nikolaos⁵,Rey-Cibati André⁶,Valladares-Delgado Mariana⁶,Turcu Andreea L.⁷,Baek Kyung-Hwa⁸,Phan Trong-Nhat⁸,Lee Hyeryon⁸,Alcaraz Mattheo⁹,Watson Savannah¹⁰,van der Watt Mariette¹⁰,Coertzen Dina¹⁰,Efstathiou Natasa¹,Chountoulesi Maria⁵,Shoen Carolyn M.¹¹,Papanastasiou Ioannis P.¹^ORCID,Brea Jose¹²^ORCID,Cynamon Michael H.¹¹,Birkholtz Lyn-Marié¹⁰,Kremer Laurent⁹¹³^ORCID,No Joo Hwan⁸,Vázquez Santiago⁷^ORCID,Benaim Gustavo⁶,Demetzos Costas⁵^ORCID,Zgurskaya Helen I.⁴^ORCID,Dick Thomas³¹⁴¹⁵,Oldfield Eric²^ORCID,Kolocouris Antonios D.¹^ORCID

Affiliation:

1. Laboratory of Medicinal Chemistry, Section of Pharmaceutical Chemistry, Department of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis-Zografou, Athens15771, Greece

2. Department of Chemistry, University of Illinois at Urbana−Champaign, Urbana, Illinois61801, United States

3. Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey07110, United States

4. Department of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma, 101 Stephenson Parkway, Norman, Oklahoma73019-5251, United States

5. Section of Pharmaceutical Technology, Faculty of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis-Zografou, Athens15771, Greece

6. Instituto de Estudios Avanzados, Caracas, Venezuela Instituto de Biología Experimental, Facultad de Ciencias, Universidad Central de Venezuela (UCV), Caracas1050, Venezuela

7. Laboratori de Química Farmacèutica (Unitat Associada al CSIC), Departament de Farmacologia, Toxicologia i Química Terapèutica, Facultat de Farmàcia i Ciències de l’Alimentació, and Institute of Biomedicine (IBUB), Universitat de Barcelona, Av. Joan XXIII, 27-31, BarcelonaE-08028, Spain

8. Host-Parasite Research Laboratory, Institut Pasteur Korea, Seongnam-si13488, Republic of Korea

9. Institut de Recherche en Infectiologie de Montpellier, CNRS UMR9004, Université de Montpellier, 1919 route de Mende, 34293Montpellier, France

10. Department of Biochemistry, Genetics and Microbiology, Institute for Sustainable Malaria Control, University of Pretoria, Hatfield, Pretoria0028, South Africa

11. Central New York Research Corporation, Veterans Affairs Medical Center, Syracuse, New York13210, United States

12. Drug Screening Platform/Biofarma Research Group, CIMUS Research Center, Departamento de Farmacoloxía, Farmacia e Tecnoloxía Farmacéutica, University of Santiago de Compostela (USC), 15782Santiago de Compostela, Spain

13. INSERM, IRIM, Montpellier34965, France

14. Department of Medical Sciences, Hackensack Meridian School of Medicine, Nutley, New Jersey07110, United States

15. Department of Microbiology and Immunology, Georgetown University, Washington, District of Columbia20007, United States

Funder

National Research Foundation of Korea

National Institute of Allergy and Infectious Diseases

Fondo Nacional de Ciencia Tecnolog?a e Innovaci?n

Minist?re de l'Enseignement Sup?rieur et de la Recherche Scientifique

Bill and Melinda Gates Foundation

Department of Science and Innovation, South Africa

South African Medical Research Council

University of Illinois Foundation