4-(3-Phenylsulfonylindol-2-yl)-1-(pyridin-2-yl)piperazinyl-methanones as Potent Inhibitors of both SARS-CoV-2 and HCoV-OC43 Viruses-Reference-Cited by-同舟云学术

4-(3-Phenylsulfonylindol-2-yl)-1-(pyridin-2-yl)piperazinyl-methanones as Potent Inhibitors of both SARS-CoV-2 and HCoV-OC43 Viruses

Published:2024-08-03 Issue:9 Volume:10 Page:3158-3175
ISSN:2373-8227
Container-title:ACS Infectious Diseases
language:en
Short-container-title:ACS Infect. Dis.

Author:

Puxeddu Michela¹^ORCID,Donalisio Manuela²^ORCID,Bugert Joachim Jakob³,Corona Angela⁴^ORCID,Cocomazzi Paolo⁵,Milani Mario⁵,Hucke Friederike³,Arduino Irene²,Esposito Francesca⁴,Moretti Paolo⁶,Ortore Maria Grazia⁶^ORCID,Nalli Marianna¹,Manetto Simone¹,Mazzoccanti Giulia¹^ORCID,Bigogno Chiara⁷,Dondio Giulio⁷^ORCID,Sciò Pietro¹,Coluccia Antonio¹^ORCID,Fracella Matteo⁸,Antonelli Guido⁸,Lembo David²^ORCID,Tramontano Enzo⁴,Silvestri Romano¹^ORCID,Mastrangelo Eloise⁵^ORCID,La Regina Giuseppe¹^ORCID

Affiliation:

1. Laboratory Affiliated to Istituto Pasteur Italia – Fondazione Cenci Bolognetti, Department of Drug Chemistry and Technologies, Sapienza University of Rome, Piazzale Aldo Moro 5, I-00185 Rome, Italy

2. Department of Clinical and Biological Sciences, University of Turin, Regione Gonzole 10, I-10043 Orbassano, Turin, Italy

3. Institut für Mikrobiologie der Bundeswehr, Neuherbergstrasse 11, D-80937 München, Germany

4. Department of Life and Environmental Sciences, University of Cagliari, S.P. 8 Monserrato, Sestu Km 0.700, I-09042 Monserrato, Italy

5. Biophysics Institute, CNR-IBF, Via Corti 12, I-20133 Milan, Italy

6. DISVA, Department of Life Sciences and Environment, Università Politecnica delle Marche, Via Brecce Bianche, I-60131 Ancona, Italy

7. Aphad SrL, Via della Resistenza 65, 20090 Buccinasco, Italy

8. Laboratory of Virology, Department of Molecular Medicine, Sapienza University of Rome, 00185 Rome, Italy

Funder

European Commission

Ministero dell?Istruzione, dell?Universit? e della Ricerca

Sapienza Universit? di Roma

Associazione Italiana per la Ricerca sul Cancro

Bundeswehr Medical Service

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.4c00108

Reference56 articles.

1. Comparative overview of emerging RNA viruses: Epidemiology, pathogenesis, diagnosis and current treatment

2. Ecology, evolution and spillover of coronaviruses from bats

3. Pathways to zoonotic spillover

4. Complexities of Viral Mutation Rates

5. Animal and human RNA viruses: genetic variability and ability to overcome vaccines