Complexities of Viral Mutation Rates-Reference-Cited by-同舟云学术

Complexities of Viral Mutation Rates

Published:2018-07-15 Issue:14 Volume:92 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Peck Kayla M.¹^ORCID,Lauring Adam S.¹²^ORCID

Affiliation:

1. Division of Infectious Diseases, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA

2. Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA

Abstract

ABSTRACT Many viruses evolve rapidly. This is due, in part, to their high mutation rates. Mutation rate estimates for over 25 viruses are currently available. Here, we review the population genetics of virus mutation rates. We specifically cover the topics of mutation rate estimation, the forces that drive the evolution of mutation rates, and how the optimal mutation rate can be context-dependent.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

Burroughs Wellcome Fund

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.01031-17

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