Antiviral Potential of the Antimicrobial Drug Atovaquone against SARS-CoV-2 and Emerging Variants of Concern

Author:

Carter-Timofte Madalina Elena1,Arulanandam Rozanne2,Kurmasheva Naziia1,Fu Kathy345,Laroche Geneviève345,Taha Zaid23,van der Horst Demi1,Cassin Lena1,van der Sluis Renée M.16,Palermo Enrico7,Di Carlo Daniele7,Jacobs David345,Maznyi Glib2,Azad Taha23,Singaravelu Ragunath2,Ren Fanghui1,Hansen Anne Louise1,Idorn Manja1,Holm Christian K.1,Jakobsen Martin R.1,van Grevenynghe Julien8,Hiscott John7,Paludan Søren R.1,Bell John C.23,Seguin Jean9,Sabourin Luc A.210,Côté Marceline345ORCID,Diallo Jean-Simon23,Alain Tommy311,Olagnier David1ORCID

Affiliation:

1. Department of Biomedicine, Aarhus University, Aarhus C 8000, Denmark

2. Center for Innovative Cancer Research, Ottawa Hospital Research Institute, Ottawa, Ontario K1H 8L6, Canada

3. Department of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Ontario K1H 8L1, Canada

4. Center for Infection, Immunity, and Inflammation, University of Ottawa, Ottawa, Ontario K1H 8L1, Canada

5. Ottawa Institute of Systems Biology, Ottawa, Ontario K1H 8L1, Canada

6. Aarhus Institute of Advanced Studies, Aarhus University, Aarhus 8000, Denmark

7. Istituto Pasteur Italia-Cenci Bolognetti Foundation, Viale Regina Elena 291, Rome 00161, Italy

8. Institut National de la Recherche Scientifique (INRS)-Centre Armand-Frappier Santé Biotechnologie, Laval, Québec H7V 1B7, Canada

9. CCFP, Dipl. Sport Med., CareMedics McArthur, 311 McArthur Avenue suite 103, Ottawa, Ontario K1L 8M3, Canada

10. Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada

11. Children’s Hospital of Eastern Ontario Research Institute, Ottawa, Ontario K1H 8L1, Canada

Funder

Government of Canada

Region Midtjylland

Det Frie Forskningsr??d

Ontario Research Foundation

European Commission

Aarhus Universitets Forskningsfond

H??rslev-Fonden

CHEO Research Institute

Lundbeckfonden

Br????drene Hartman fond

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

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