1,3-Dioxane-Linked Bacterial Topoisomerase Inhibitors with Enhanced Antibacterial Activity and Reduced hERG Inhibition-Reference-Cited by-同舟云学术

1,3-Dioxane-Linked Bacterial Topoisomerase Inhibitors with Enhanced Antibacterial Activity and Reduced hERG Inhibition

Published:2019-05-01 Issue:7 Volume:5 Page:1115-1128
ISSN:2373-8227
Container-title:ACS Infectious Diseases
language:en
Short-container-title:ACS Infect. Dis.

Author:

Li Linsen¹,Okumu Antony A.¹,Nolan Sheri²,English Anthony³,Vibhute Sandip¹,Lu Yanran¹,Hervert-Thomas Katherine⁴,Seffernick Justin T.⁵,Azap Lovette¹,Cole Serena L.⁶,Shinabarger D.⁶,Koeth Laura M.⁷,Lindert Steffen⁵^ORCID,Yalowich Jack C.³,Wozniak Daniel J.²⁸,Mitton-Fry Mark J.¹^ORCID

Affiliation:

1. Division of Medicinal Chemistry and Pharmacognosy, The Ohio State University, 500 West 12th Avenue, Columbus, Ohio 43210, United States

2. Microbial Infection and Immunity, The Ohio State University, 460 West 12th Avenue, Columbus, Ohio 43210, United States

3. Division of Pharmacology, The Ohio State University, 500 West 12th Avenue, Columbus, Ohio 43210, United States

4. Department of Chemistry, Ohio Wesleyan University, 61 South Sandusky Street, Delaware, Ohio 43015, United States

5. Department of Chemistry and Biochemistry, The Ohio State University, 100 West 18th Avenue, Columbus, Ohio 43210, United States

6. Micromyx, 4717 Campus Drive, Kalamazoo, Michigan 49008, United States

7. Laboratory Specialists, Inc., 26214 Center Ridge Road, Westlake, Ohio 44145, United States

8. Department of Microbiology, The Ohio State University, 484 West 12th Avenue, Columbus, Ohio 43210, United States

Funder

Cystic Fibrosis Foundation

Ohio State University

College of Pharmacy, Ohio State University

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

Link

https://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.8b00375

Reference59 articles.

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5. Methicillin-Resistant Staphylococcus aureus Therapy: Past, Present, and Future

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