Nonsteroidal Anti-Inflammatory Drug-Induced Leaky Gut Modeled Using Polarized Monolayers of Primary Human Intestinal Epithelial Cells

Author:

Bhatt Aadra P.1,Gunasekara Dulan B.1,Speer Jennifer1,Reed Mark I.1,Peña Alexis N.1,Midkiff Bentley R.2,Magness Scott T.34,Bultman Scott J.56,Allbritton Nancy L.136ORCID,Redinbo Matthew R.167ORCID

Affiliation:

1. Department of Chemistry, University of North Carolina, 250 Bell Tower Drive, Chapel Hill, North Carolina 27599-3290, United States

2. Translational Pathology Laboratory, Lineberger Comprehensive Cancer Center, University of North Carolina, 160 North Medical Drive, Chapel Hill, North Carolina 27599-7525, United States

3. Department of Biomedical Engineering, University of North Carolina, Chapel Hill, North Carolina 27599, United States, and North Carolina State University, Raleigh, North Carolina 27607, United States

4. Departments of Medicine, Cell Biology and Physiology, University of North Carolina, 111 Mason Farm Road, Chapel Hill, North Carolina 27599-7032, United States

5. Department of Genetics, University of North Carolina, 120 Mason Farm Road, Chapel Hill, North Carolina 27599-7264, United States

6. Lineberger Comprehensive Cancer Center, University of North Carolina, 450 West Drive, Chapel Hill, North Carolina 27599, United States

7. Departments of Biochemistry and Biophysics, and Microbiology and Immunology, and the Integrated Program for Biological and Genome Science, University of North Carolina, 250 Bell Tower Drive, Chapel Hill, North Carolina 27599-3290, United States

Funder

National Cancer Institute

National Institute of Diabetes and Digestive and Kidney Diseases

U.S. Department of Agriculture

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

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