N-Myristoylation as a Drug Target in Malaria: Exploring the Role of N-Myristoyltransferase Substrates in the Inhibitor Mode of Action
Author:
Affiliation:
1. Malaria Parasitology, The Francis Crick Institute, 1 Midland Road, NW1 1AT London, United Kingdom
2. Department of Chemistry, Imperial College London, Imperial College Road, SW7 2AZ London, United Kingdom
Funder
Medical Research Council
Wellcome Trust
Cancer Research UK
Publisher
American Chemical Society (ACS)
Subject
Infectious Diseases
Link
https://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.7b00203
Reference82 articles.
1. Antimalarial drug resistance: linking Plasmodium falciparum parasite biology to the clinic
2. A Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Infants
3. Protein myristoylation in health and disease
4. Validation of N-myristoyltransferase as an antimalarial drug target using an integrated chemical biology approach
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