Medetomidine Analogs as α2-Adrenergic Ligands. 3. Synthesis and Biological Evaluation of a New Series of Medetomidine Analogs and Their Potential Binding Interactions with α2-Adrenoceptors Involving a “Methyl Pocket”-Reference-Cited by-同舟云学术

Medetomidine Analogs as α2-Adrenergic Ligands. 3. Synthesis and Biological Evaluation of a New Series of Medetomidine Analogs and Their Potential Binding Interactions with α2-Adrenoceptors Involving a “Methyl Pocket”

Published:1997-09-01 Issue:19 Volume:40 Page:3014-3024
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhang Xiaoyan¹,De Los Angeles Joseph E.¹,He Mei-Ying¹,Dalton James T.¹,Shams Gamal¹,Lei Longping¹,Patil Popat N.¹,Feller Dennis R.¹,Miller Duane D.¹,Hsu Fu-Lian¹

Affiliation:

1. Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee, 847 Monroe Avenue, Room 327, Memphis, Tennessee 38163

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm960642q

Reference22 articles.

1. Dexmedetomidine, a novel alpha2-adrenergic agonist. A review of its pharmacodynamic characteristics

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