Classification of Inhibitors of Hepatic Organic Anion Transporting Polypeptides (OATPs): Influence of Protein Expression on Drug–Drug Interactions-Reference-Cited by-同舟云学术

Classification of Inhibitors of Hepatic Organic Anion Transporting Polypeptides (OATPs): Influence of Protein Expression on Drug–Drug Interactions

Published:2012-05-15 Issue:10 Volume:55 Page:4740-4763
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Karlgren Maria¹²,Vildhede Anna¹,Norinder Ulf¹³,Wisniewski Jacek R.⁴,Kimoto Emi⁵,Lai Yurong⁵,Haglund Ulf⁶,Artursson Per¹²

Affiliation:

1. Department of Pharmacy, Uppsala University, 751 23 Uppsala, Sweden

2. Uppsala University Drug Optimization and Pharmaceutical Profiling Platform—a node of the Chemical Biology Consortium Sweden (CBCS), Department of Pharmacy, Uppsala University, 751 23 Uppsala, Sweden

3. AstraZeneca R&D, 151 85 Södertälje, Sweden

4. Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried D 82152, Germany

5. Pfizer World Wide R&D, Groton, Connecticut 06340, United States

6. Department of Surgical Sciences, Section Surgery, Uppsala University, 751 85 Uppsala, Sweden

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm300212s

Reference92 articles.

1. Expression of Thirty-six Drug Transporter Genes in Human Intestine, Liver, Kidney, and Organotypic Cell Lines

2. Simultaneous Absolute Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases as a Novel Approach for the Characterization of Individual Human Liver: Comparison with mRNA Levels and Activities

3. Membrane transporters in drug development

4. Impact of OATP transporters on pharmacokinetics

5. SLCO1B1Variants and Statin-Induced Myopathy — A Genomewide Study

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