Identification of Protein–Ligand Binding Sites by the Level-Set Variational Implicit-Solvent Approach

Author:

Guo Zuojun1,Li Bo2,Cheng Li-Tien3,Zhou Shenggao2,McCammon J. Andrew4,Che Jianwei1

Affiliation:

1. Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121, United States

2. Department of Mathematics and Center for Theoretical Biological Physics, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093-0112, United States

3. Department of Mathematics, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093-0112, United States

4. Department of Chemistry and Biochemistry, Department of Pharmacology, Howard Hughes Medical Institute, and Center for Theoretical Biological Physics, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093-0365, United States

Funder

Howard Hughes Medical Institute

Division of Mathematical Sciences

National Institute of General Medical Sciences

Division of Physics

Genomics Institute of the Novartis Research Foundation

Publisher

American Chemical Society (ACS)

Subject

Physical and Theoretical Chemistry,Computer Science Applications

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