Discovery of Novel Chemotypes to a G-Protein-Coupled Receptor through Ligand-Steered Homology Modeling and Structure-Based Virtual Screening-Reference-Cited by-同舟云学术

Discovery of Novel Chemotypes to a G-Protein-Coupled Receptor through Ligand-Steered Homology Modeling and Structure-Based Virtual Screening

Published:2008-01-17 Issue:3 Volume:51 Page:581-588
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Cavasotto Claudio N.¹,Orry Andrew J. W.¹,Murgolo Nicholas J.¹,Czarniecki Michael F.¹,Kocsi Sue Ann¹,Hawes Brian E.¹,O’Neill Kim A.¹,Hine Heather¹,Burton Marybeth S.¹,Voigt Johannes H.¹,Abagyan Ruben A.¹,Bayne Marvin L.¹,Monsma Frederick J.¹

Affiliation:

1. MolSoft LLC, 3366 North Torrey Pines Court, Suite 300, La Jolla, California 92037, Departments of Discovery Technologies, Chemical Technologies, Cardiovascular Biology, Structural Chemistry, and New Lead Discovery, Schering-Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, and The Scripps Research Institute, 10550 North Torrey Pines Court, La Jolla, California 92037

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm070759m

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5. Cloning of a Novel G Protein-Coupled Receptor, SLT, a Subtype of the Melanin-Concentrating Hormone Receptor

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