1. Institute of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung, 202 Taiwan; Institute of Plant and Microbial Biology, Academia Sinica, Nankang, Taipei, 11529 Taiwan; Department of Biotechnology, Ming Chuan University, Gweishan District, Taoyuan, 333 Taiwan; and Department of Food Science and Biotechnology, National Chung Hsing University, Taichung 402 Taiwan